发明授权
- 专利标题: Benzoguanamine derivatives, their production and pharmaceutical compositions containing the same
- 专利标题(中): 苯胍胺衍生物,其生产和含有相同的药物组合物
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申请号: US266483申请日: 1981-05-22
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公开(公告)号: US4333933A公开(公告)日: 1982-06-08
- 发明人: Shingo Matsumura , Hiroshi Enomoto , Yoshiaki Aoyagi , Yoshihisa Shibata
- 申请人: Shingo Matsumura , Hiroshi Enomoto , Yoshiaki Aoyagi , Yoshihisa Shibata
- 申请人地址: JPX
- 专利权人: Nippon Shinyaku Co., Ltd.
- 当前专利权人: Nippon Shinyaku Co., Ltd.
- 当前专利权人地址: JPX
- 优先权: JPX55/75875 19800604
- 主分类号: C07D401/12
- IPC分类号: C07D401/12 ; A61K31/53 ; A61P25/04 ; C07D251/16 ; C07D251/18 ; C07D251/48 ; A61K31/44
摘要:
Novel 2-amino-4-nicotinoylamino-6-halogenophenyl-s-triazines and acid addition salts thereof, possessing strong anti-inflammatory action when the phenyl group is mono- or di-halogen substituted. The compounds are formulated into pharmaceutical compositions in bulk or dosage form, and are administered to humans and animals having inflammatory conditions or disorders until the same are reduced or overcome. The novel compounds are prepared by various procedures such as reacting a benzoguanamine which is halogen-substituted with an active derivative of nicotinic acid, and recovering the 2-amino-4-nicotinoylamino-6-halogenophenyl-s-triazines thus formed.
公开/授权文献
- US5490929A Cleaner for atomizer 公开/授权日:1996-02-13