发明授权
- 专利标题： Prostanoic acid derivatives and their preparation
- 专利标题（中）： 前列腺酸衍生物及其制备
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申请号： US256369申请日： 1981-04-22
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公开(公告)号： US4359467A公开(公告)日： 1982-11-16
- 发明人: Helmut Vorbruggen , Norbert Schwarz , Olaf Loge , Walter Elger
- 申请人： Helmut Vorbruggen , Norbert Schwarz , Olaf Loge , Walter Elger
- 申请人地址： DEX Bergkamen and Berlin
- 专利权人： Schering Aktiengesellschaft
- 当前专利权人： Schering Aktiengesellschaft
- 当前专利权人地址： DEX Bergkamen and Berlin
- 优先权： DEX2635985 19760806
- 主分类号： A61K31/27
- IPC分类号： A61K31/27 ; A61K31/19 ; A61K31/215 ; A61K31/255 ; A61K31/275 ; A61P43/00 ; C07C51/38 ; C07C57/03 ; C07C57/13 ; C07C57/52 ; C07C67/00 ; C07C401/00 ; C07C405/00 ; C07D307/935 ; C07F9/535 ; C07C177/00 ; A61K31/557
摘要：
Prostanoic acid derivatives of the formula ##STR1## wherein R.sub.1 is an acid, ester, amide or hydroxyalkylene group; R.sub.2 and R.sub.3 are H or alkyl; R.sub.4 and R.sub.5 are both CH.sub.3 or one is Cl and the other is CH.sub.3 ; A is CH.sub.2 CH.sub.2 or --CH.dbd.CH; B is CH.sub.2 CH.sub.2, trans- ##STR2## W is free or functionally modified hydroxyalkylene or carbonyl; Z is free or functionally modified hydroxymethylene or carbonyl; X Y is either ##STR3## or, when Z is free or functionally modified hydroxymethylene, ##STR4## or, when Z is free or functionally modified carbonyl, --CH.dbd.CH--, R.sub.12 being H, CH.sub.3, CN or free or functionally modified hydroxy; and physiologically acceptable salts thereof when R.sub.1 is an acid group, possess pharmacological activity, including abortion triggering activity.
公开/授权文献
- US6057414A Process of plasma treating polymer materials 公开/授权日：2000-05-02
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