发明授权
US4376771A 6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic agents
containing said compounds
失效
6-(对酰氨基苯基)-4,5-二氢哒嗪-3-酮和含有所述化合物的治疗剂
- 专利标题: 6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic agents containing said compounds
- 专利标题(中): 6-(对酰氨基苯基)-4,5-二氢哒嗪-3-酮和含有所述化合物的治疗剂
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申请号: US224939申请日: 1981-01-14
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公开(公告)号: US4376771A公开(公告)日: 1983-03-15
- 发明人: Rolf Lebkuecher , Marco Thyes , Horst Koenig , Hans D. Lehmann , Josef Gries , Dieter Lenke , Johannes Kunze
- 申请人: Rolf Lebkuecher , Marco Thyes , Horst Koenig , Hans D. Lehmann , Josef Gries , Dieter Lenke , Johannes Kunze
- 申请人地址: DEX
- 专利权人: BASF Aktiengesellschaft
- 当前专利权人: BASF Aktiengesellschaft
- 当前专利权人地址: DEX
- 优先权: DEX2727481 19770618
- 主分类号: C07D237/00
- IPC分类号: C07D237/00 ; A61K31/50 ; A61P7/02 ; A61P9/12 ; C07D237/04
摘要:
6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl of 1 to 3 carbon atoms and R.sup.2, if R.sup.1 is hydrogen, is halogen-substituted alkyl of 3 to 6 carbon atoms or .beta.-haloethyl or, if R.sup.1 is alkyl of 1 to 3 carbon atoms, is halogen-substituted alkyl of 1 to 6 carbon atoms, their manufacture, and therapeutic agents which contain, as the active ingredient, a compound of the formula I, where R.sup.2 may also be halomethyl or .alpha.-haloethyl if R.sup.1 is hydrogen. These compounds may be used as anti-hypertensive agents and for the prophylaxis and therapy of thromboembolic disorders.
公开/授权文献
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