发明授权
US4389416A Diphenyl ether, diphenyl thioether and diphenyl methane phenol mannich
bases
失效
二苯基醚，二苯基硫醚和二苯甲烷苯酚甘露醇碱
- 专利标题： Diphenyl ether, diphenyl thioether and diphenyl methane phenol mannich bases
- 专利标题（中）： 二苯基醚，二苯基硫醚和二苯甲烷苯酚甘露醇碱
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申请号： US310164申请日： 1981-10-09
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公开(公告)号： US4389416A公开(公告)日： 1983-06-21
- 发明人: Jacob J. Plattner
- 申请人： Jacob J. Plattner
- 申请人地址： IL North Chicago
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL North Chicago
- 主分类号： C07C205/38
- IPC分类号： C07C205/38 ; A61K31/215 ; C07C91/16 ; C07C101/30 ; C07C103/29
摘要：
Described are compounds of the formula ##STR1## wherein R is hydrogen, loweralkyl, aminomethyl or halo; R.sub.1 is carboxy, carboxyloweralkyl, aminocarbonyl, hydroxymethyl, anilinomethyl, or aminomethyl; A is oxygen, CH.sub.2, Sulfur or a single bond; X is oxygen, CH.sub.2, sulfur or sulfoxide; and Y is hydrogen, loweralkyl or halo and may be the same or different, and pharmaceutically acceptable salts thereof.The compounds are effective as diuretic agents.
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