发明授权
US4411909A [(2-Oxo-3-tetrahydrothienylcarbamoyl)-alkylthio] acetic acids, their
salts and esters, a process for preparation thereof and the
pharmaceutical compositions containing same
失效
[(2-氧代-3-四氢噻吩基氨基甲酰基) - 烷硫基]乙酸,其盐和酯,其制备方法和含有它们的药物组合物
- 专利标题: [(2-Oxo-3-tetrahydrothienylcarbamoyl)-alkylthio] acetic acids, their salts and esters, a process for preparation thereof and the pharmaceutical compositions containing same
- 专利标题(中): [(2-氧代-3-四氢噻吩基氨基甲酰基) - 烷硫基]乙酸,其盐和酯,其制备方法和含有它们的药物组合物
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申请号: US358370申请日: 1982-03-15
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公开(公告)号: US4411909A公开(公告)日: 1983-10-25
- 发明人: Jacques Gonella
- 申请人: Jacques Gonella
- 申请人地址: CHX
- 专利权人: Refarmed, Recherches Pharmaceutiques et Medicales, S.A.
- 当前专利权人: Refarmed, Recherches Pharmaceutiques et Medicales, S.A.
- 当前专利权人地址: CHX
- 优先权: FRX8105496 19810319
- 主分类号: A61K31/38
- IPC分类号: A61K31/38 ; A61K31/381 ; A61P11/00 ; A61P11/10 ; A61P27/16 ; C07D333/36
摘要:
The present invention relates to [(2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio]-acetic acids, their salts and esters of formula: ##STR1## in which n is 0 or 1, one of the substituents R.sub.1 and R.sub.2 is a hydrogen atom or a methyl group and the other represents a group -S-CH.sub.2 -COOR.sub.3, where R.sub.3 is a hydrogen atom or an alkali metal or a lower alkyl group or a group: ##STR2## It also relates to a process for preparing said acids, salts and esters, and to the drugs containing same.
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