发明授权
US4412083A Process for producing solanone, norsolanadione and intermediates therefor
失效
制备索罗酮,二酰甘油和其中间体的方法
- 专利标题: Process for producing solanone, norsolanadione and intermediates therefor
- 专利标题(中): 制备索罗酮,二酰甘油和其中间体的方法
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申请号: US357158申请日: 1982-03-11
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公开(公告)号: US4412083A公开(公告)日: 1983-10-25
- 发明人: Kenneth K. Light , William L. Schreiber , Joseph A. McGhie , Ronald P. Schreck , Takao Yoshida , Loren B. Schreiber , Ranya Muralidhara
- 申请人: Kenneth K. Light , William L. Schreiber , Joseph A. McGhie , Ronald P. Schreck , Takao Yoshida , Loren B. Schreiber , Ranya Muralidhara
- 申请人地址: NY New York
- 专利权人: International Flavors & Fragrances Inc.
- 当前专利权人: International Flavors & Fragrances Inc.
- 当前专利权人地址: NY New York
- 主分类号: A23L27/20
- IPC分类号: A23L27/20 ; A24B15/32 ; C07C45/42 ; C07C45/51 ; C07C45/59 ; C07C45/66 ; C07D295/02 ; C07D295/03 ; C07D295/145 ; C07D295/155 ; C07D309/28 ; C07D317/30 ; C07C119/12
摘要:
Described is a process for preparing solanone and norsolanadione using chemical intermediates defined according to the generic structure: ##STR1## wherein X is one of the moieties: ##STR2## wherein R represents hydrogen or methyl; wherein Y represents one of the structures: ##STR3## wherein one of the dashed lines represents a carbon-carbon single bond and the other of the dashed lines represents a carbon-carbon double bond; with the provisos that:(i) when Y is the moiety having the structure: ##STR4## then X is the moiety having the structure: ##STR5## (ii) when X is the moiety having the structure: ##STR6## then Y is the moiety having the structure:--C.tbd.N]In preparing solanone, the compound having the structure: ##STR7## or a mixture of compounds defined according to the structure: ##STR8## is reacted with methyl lithium and the resulting intermediate is hydrolyzed and the resulting compound is dehydrated. In producing the norsolanadione, the compound having the structure: ##STR9## or a mixture of compounds according to the structure: ##STR10## is reacted with ethylene glycol or propylene glycol thereby forming a ketal and the resulting ketal is reacted with methyl lithium and the resulting intermediate is then hydrolyzed in the presence of acid.