发明授权
- 专利标题: Bicyclothiazoles
- 专利标题(中): 双环噻唑
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申请号: US420157申请日: 1982-09-20
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公开(公告)号: US4443610A公开(公告)日: 1984-04-17
- 发明人: Fu-chih Huang
- 申请人: Fu-chih Huang
- 申请人地址: NY Tarrytown
- 专利权人: USV Pharmaceutical Corporation
- 当前专利权人: USV Pharmaceutical Corporation
- 当前专利权人地址: NY Tarrytown
- 主分类号: C07C37/055
- IPC分类号: C07C37/055 ; C07C39/23 ; C07C43/215 ; C07C205/25 ; C07D263/52 ; C07D263/60 ; C07D265/34 ; C07D413/04 ; C07D277/84 ; A61K31/415
摘要:
Bicyclothiazoles having the structure: ##STR1## wherein n is 3, 4, or 5R.sub.1 is hydrogen or alkyl,R.sub.2 is hydrogen, alkyl, hydroxyl, alkoxy, cyano, phenyl, carboxyl, tetrazole, or halogen,R.sub.3 is tetrazole, carboxamide or ##STR2## wherein Z is oxygen, sulfur, or NH andR.sub.4 is H, alkali metal, ammonium, alkyl, alkoxyalkyl, aryl, or aralkyl,are novel and useful as antiallergic agents. The compounds are formulated with a pharmaceutical carrier for oral, parental, inhalational, or rectal means of administration.
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