发明授权
- 专利标题: Carbamate intermediates for bronchospasmolytics
- 专利标题(中): 用于支气管痉挛症的氨基甲酸酯中间体
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申请号: US395650申请日: 1982-07-06
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公开(公告)号: US4451663A公开(公告)日: 1984-05-29
- 发明人: O. A. Torsten Olsson , Leif A. Svensson , Kjell I. L. Wetterlin
- 申请人: O. A. Torsten Olsson , Leif A. Svensson , Kjell I. L. Wetterlin
- 申请人地址: SEX Lund
- 专利权人: Aktiebolaget Draco
- 当前专利权人: Aktiebolaget Draco
- 当前专利权人地址: SEX Lund
- 优先权: GBX8022439 19800709; GBX8116441 19810529
- 主分类号: C07C215/60
- IPC分类号: C07C215/60 ; A61K20060101 ; A61K31/137 ; A61K31/27 ; A61K31/375 ; A61P11/00 ; A61P11/08 ; A61P13/02 ; A61P15/00 ; C07C20060101 ; C07C67/00 ; C07C215/00 ; C07C215/34 ; C07C239/00 ; C07C269/06 ; C07C271/44 ; C07C271/58 ; C07C125/04 ; C07C125/067
摘要:
New bronchospasmolytically active compounds exhibiting long duration of action and reduced undesired side effects of the structural formula ##STR1## and therapeutically acceptable salts thereof, in which formula R is selected from the group consisting of --C(CH.sub.3).sub.3, ##STR2## R.sup.1 is selected from the group consisting of H and R.sup.2, R.sup.2 represents the radical of the formula ##STR3## wherein R.sup.3 is selected from the group consisting of(a) H(b) alkyl groups containing 1-3 carbon atoms ##STR4## wherein R.sup.5 is selected from the group consisting of(a) OH(b) alkoxy groups containing 1-3 carbon atoms and whereinR.sup.4 is selected from the group consisting of(a) H(b) alkyl groups containing 1-3 carbon atoms, with the proviso that R.sup.3 and R.sup.4 are combined as follows:______________________________________ when R.sup.3 is then R.sup.4 is ______________________________________ H H alkyl group of 1-3 carbon atoms H or an alkyl group of 1-3 carbon atoms ##STR5## H ______________________________________ processes for the preparation thereof, chemical intermediates at their preparation, pharmaceutical preparations containing them, and their medicinal use.
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