发明授权
- 专利标题: Preparation of ortho-aminobenzotrifluoride
- 专利标题(中): 邻氨基三氟甲苯的制备
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申请号: US530152申请日: 1983-09-07
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公开(公告)号: US4469890A公开(公告)日: 1984-09-04
- 发明人: John P. Chupp , Thomas E. Neumann , Michael J. Miller
- 申请人: John P. Chupp , Thomas E. Neumann , Michael J. Miller
- 申请人地址: MO St. Louis
- 专利权人: Monsanto Company
- 当前专利权人: Monsanto Company
- 当前专利权人地址: MO St. Louis
- 主分类号: C07C17/12
- IPC分类号: C07C17/12 ; C07C205/12 ; C07C85/00 ; C07C85/11
摘要:
This invention relates to a process for the preparation of ortho-aminobenzotrifluoride (OABT) from benzotrifluoride (BTF). The process provides an overall route employing non-isolation of intermediates which can be run smoothly and which results in the preparation of OABT in high yields with less contamination. This process includes a catalytic halogenation step in which BTF is converted to meta-halo BTF and other mono and di-halo isomers of BTF followed by nitration in the same reaction vessel under conditions which do not favor nitration of the di-halo isomers of BTF to produce a mixture which predominates in 5-halo-2-nitro BTF. In the final step the 5-halo-2-nitro BTF present is reduced and hydrodehalogenated with H.sub.2 in the presence of a catalyst to form OABT. Recyclable BTF is also obtained from the final reaction.
公开/授权文献
- US5792526A Multilayer film and container 公开/授权日:1998-08-11
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