发明授权
US4473566A 7-(.alpha.,
.alpha.-Disubstituted-acetamido)-3-substituted-3-cephem-4-carboxylic
acids
失效
7-(α,α-二取代 - 乙酰氨基)-3-取代-3-头孢烯-4-羧酸
- 专利标题: 7-(.alpha., .alpha.-Disubstituted-acetamido)-3-substituted-3-cephem-4-carboxylic acids
- 专利标题(中): 7-(α,α-二取代 - 乙酰氨基)-3-取代-3-头孢烯-4-羧酸
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申请号: US203564申请日: 1980-10-31
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公开(公告)号: US4473566A公开(公告)日: 1984-09-25
- 发明人: Takao Takaya , Takashi Masugi , Hisashi Takasugi , Hiromu Kochi
- 申请人: Takao Takaya , Takashi Masugi , Hisashi Takasugi , Hiromu Kochi
- 申请人地址: JPX Osaka
- 专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX50-15191 19750204; JPX50-37647 19750327; JPX50-48833 19750421; JPX50-78294 19750623; JPX50-83867 19750707
- 主分类号: C07C45/00
- IPC分类号: C07C45/00 ; C07C45/71 ; C07C59/84 ; C07C59/88 ; C07C59/90 ; C07C205/45 ; C07C205/56 ; C07D333/24 ; A61K31/545
摘要:
7-(.alpha.,.alpha.-disubstituted-acetamido)-3-substituted-3-cephem-4-carboxylic acids having antibacterial properties and the following formula are disclosed: ##STR1## wherein R.sup.1 is hydrogen, halogen, hydroxy, nitro, lower alkoxy or acylamino, R.sup.2 is hydrogen or acyl andR.sup.3 is lower alkanoyloxy, carbamoyloxy which may have lower alkyl, aryl or protective group for amino or a heterocyclicthio which may have lower alkyl.
公开/授权文献
- US4878288A Press 公开/授权日:1989-11-07