发明授权
- 专利标题: ACE inhibitors produced from Nocardia orientalis
- 专利标题(中): 由诺卡氏菌产生的ACE抑制剂
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申请号: US547151申请日: 1983-10-31
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公开(公告)号: US4474693A公开(公告)日: 1984-10-02
- 发明人: Pushpa Singh , Karen Bush , Dorothy S. Slusarchyk
- 申请人: Pushpa Singh , Karen Bush , Dorothy S. Slusarchyk
- 申请人地址: NJ Princeton
- 专利权人: E. R. Squibb & Sons, Inc.
- 当前专利权人: E. R. Squibb & Sons, Inc.
- 当前专利权人地址: NJ Princeton
- 主分类号: C07K9/00
- IPC分类号: C07K9/00 ; C07C103/52 ; C07G7/00
摘要:
N.sup.2 -[N-(N-acetylmuramoyl)-L-alanyl]-N-(5,6-diamino-1-carboxy-6-oxohexyl)-D-.alpha.-glutamine, N.sup.2 -[N-(N-acetylmuramoyl)-L-alanyl]-N-[5,6-diamino-1-[[1-[(1-carboxyethyl)carbamoyl]ethyl]carbamoyl]-6-oxohexyl]-D-.alpha.-glutamine and EM5556C are obtained as a mixture by cultivating a strain of the microorganism Nocardia orientalis A.T.C.C. No. 39444.
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