A two wheel vehicle comprising a vehicle body having a front wheel and a rear wheel with an internal combustion engine mounted on the mid portion of the frame is provided. The engine is provided with a supercharger having an exhaust turbine provided on an exhaust passage side thereof and a compressor provided on an intake passage side thereof and arranged to move with the turbine. The supercharger is positioned in a space defined by the engine and a supporting frame which supports the engine and is interposed between the engine and the front wheel. The defined space is remote from the driver so that the driver is not affected by the supercharger. The supercharger may be mounted on the supporting frame so that it is protected against external frontal or lateral forces.