发明授权
- 专利标题: Succinimide derivatives, compositions and method of use
- 专利标题(中): 琥珀酰亚胺衍生物,组合物和使用方法
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申请号: US446047申请日: 1982-12-01
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公开(公告)号: US4507303A公开(公告)日: 1985-03-26
- 发明人: Kikuo Ishizumi , Fujio Antoku , Yukio Asami
- 申请人: Kikuo Ishizumi , Fujio Antoku , Yukio Asami
- 申请人地址: JPX Osaka
- 专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人地址: JPX Osaka
- 优先权: JPX56-208379 19811222; JPX57-95763 19820603
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61K31/505 ; C07D209/76 ; C07D401/12 ; C07D403/02 ; C07D403/06 ; C07D403/12 ; C07D491/18 ; C07D403/04 ; C07D403/14
摘要:
Succinimide derivatives representable by the following formula: ##STR1## wherein X and Y are combined to form a group of the formula: ##STR2## (wherein A is an oxygen atom, a methylene group or an ethylene group and a full line accompanying a broken line ( ) is a single bond or a double bond) and Z is a hydrogen atom or, X and Z are combined to form a group of the formula: ##STR3## (wherein A and a full line are each as defined above) and Y is a hydrogen atom, R is a phenyl group, optionally substituted with halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or trifluoromethyl, a 2-pyridyl group or a 2-pyrimidinyl group and n is an integer of 3 or 4, and pharmaceutically acceptable acid addition salts thereof, which are useful as antianxious substances.
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