发明授权
- 专利标题： Indacrinone having enhanced uricosuric
- 专利标题（中）： 茚曲坦酮具有增强的尿酸
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申请号： US463685申请日： 1983-02-03
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公开(公告)号： US4510322A公开(公告)日： 1985-04-09
- 发明人: Edward H. Blaine , Edward J. Cragoe, Jr. , Ralph F. Hirschmann , John F. Nancarrow, deceased , by Elisabeth M. Nancarrow, executrix , Jonathan A. Tobert
- 申请人： Edward H. Blaine , Edward J. Cragoe, Jr. , Ralph F. Hirschmann , John F. Nancarrow, deceased , by Elisabeth M. Nancarrow, executrix , Jonathan A. Tobert
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K38/04 ; C07C59/80
摘要：
The uricosuric and diuretic properties of indacrinone, [6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid, are carefully balanced for maximum therapeutic benefit by manipulation of the proportion of (+) and (-) enantiomers in the final product within critical limits.
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