发明授权
US4521537A Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine]
compounds and their use as antihypertensive agents
失效
螺[2H-1,4-苯并二氧杂环庚烯-3（5H）4'-哌啶和-3'-吡咯烷]化合物及其作为抗高血压剂的用途
- 专利标题： Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds and their use as antihypertensive agents
- 专利标题（中）： 螺[2H-1,4-苯并二氧杂环庚烯-3（5H）4'-哌啶和-3'-吡咯烷]化合物及其作为抗高血压剂的用途
-
申请号： US595781申请日： 1984-04-02
-
公开(公告)号： US4521537A公开(公告)日： 1985-06-04
- 发明人: Raymond W. Kosley, Jr. , Robert J. Cherill
- 申请人： Raymond W. Kosley, Jr. , Robert J. Cherill
- 申请人地址： NJ Somerville
- 专利权人： Hoechst-Roussel Pharmaceuticals Incorporated
- 当前专利权人： Hoechst-Roussel Pharmaceuticals Incorporated
- 当前专利权人地址： NJ Somerville
- 主分类号： C07D211/48
- IPC分类号： C07D211/48 ; C07D491/10 ; C07D491/113 ; A61K31/455
摘要：
Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.
公开/授权文献
- US5926386A Configuration based cooling fan speed control 公开/授权日：1999-07-20
信息查询
