发明授权
US4539203A CL-1577D And CL-1577E antibiotic/antitumor compounds, their production
and use
失效
CL-1577D和CL-1577E抗生素/抗肿瘤化合物,其生产和使用
- 专利标题: CL-1577D And CL-1577E antibiotic/antitumor compounds, their production and use
- 专利标题(中): CL-1577D和CL-1577E抗生素/抗肿瘤化合物,其生产和使用
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申请号: US670240申请日: 1984-11-13
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公开(公告)号: US4539203A公开(公告)日: 1985-09-03
- 发明人: Alex J. Brankiewicz , Richard H. Bunge , James C. French , Gerard C. Hokanson , Timothy R. Hurley , John P. Schaumberg
- 申请人: Alex J. Brankiewicz , Richard H. Bunge , James C. French , Gerard C. Hokanson , Timothy R. Hurley , John P. Schaumberg
- 申请人地址: Morris Plains, NJ
- 专利权人: Warner-Lambert Company
- 当前专利权人: Warner-Lambert Company
- 当前专利权人地址: Morris Plains, NJ
- 主分类号: C07G11/00
- IPC分类号: C07G11/00 ; A61K35/74 ; A61P31/04 ; A61P35/00 ; C12P1/06 ; C12R1/03
摘要:
Compounds CL-1577D and CL-1577E are prepared by cultivation of a purified isolate of Actinomycete designated ATCC 39363 in a culture medium having assimilable sources of carbon and nitrogen. The compounds are effective antimicrobial agents and possess cytotoxic activity against L1210 murine leukemia cells and P388 murine leukemia cells.
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