发明授权
- 专利标题: Tetrahydrocarbazole derivatives
- 专利标题(中): 四氢咔唑衍生物
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申请号: US568310申请日: 1984-01-04
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公开(公告)号: US4547576A公开(公告)日: 1985-10-15
- 发明人: Hans-Heinrich Hausberg , Henning Bottcher , Rudolf Gottschlich , Christoph Seyfried , Klaus-Otto Minck
- 申请人: Hans-Heinrich Hausberg , Henning Bottcher , Rudolf Gottschlich , Christoph Seyfried , Klaus-Otto Minck
- 申请人地址: DEX Darmstadt
- 专利权人: Merck Patent Gesellschaft mit beschrankter Haftung
- 当前专利权人: Merck Patent Gesellschaft mit beschrankter Haftung
- 当前专利权人地址: DEX Darmstadt
- 优先权: DEX3300094 19830104; DEX3336643 19831008
- 主分类号: C07D401/06
- IPC分类号: C07D401/06 ; C07D405/14 ; C07D409/14 ; C07D491/04 ; C07D491/056
摘要:
Tetrahydrocarbazole derivatives of the general formula I ##STR1## in which Thc is a 1,2,3,4-tetrahydro-3-carbazolyl radical which can be substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, the two radicals Y are each H or together are a C--C bond, one radical Z is Ar and the other radical Z is H, A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- and Ar is a phenyl group which is unsubstituted or substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, or is a 2- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts have effects on the central nervous system.
公开/授权文献
- US5976832A DNA encoding novel calcium-binding proteins 公开/授权日:1999-11-02
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