发明授权
- 专利标题： Antibiotics
- 专利标题（中）： 抗生素
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申请号： US33045681申请日： 1981-12-14
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公开(公告)号： US4560552C1公开(公告)日： 2001-10-16
- 发明人: COLE MARTIN , HOWARTH THOMAS T , READING CHRISTOPHER
- 申请人： BEECHAM GROUP LTD
- 优先权： GB1741074 1974-04-20; GB2771574 1974-06-21; GB4365174 1974-10-09; GB5352574 1974-12-11
- 主分类号： A61K31/42
- IPC分类号： A61K31/42 ; A61K31/43 ; A61P31/04 ; C07D503/00 ; C12N9/99 ; C12P1/06 ; C12P17/18 ; C12P37/04 ; A61K35/00
摘要：
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): (I) In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of beta -lactam antibiotics against many beta -lactamase producing bacteria.
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