发明授权
- 专利标题: Thienothiazole derivatives
- 专利标题(中): 噻吩噻唑衍生物
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申请号: US649898申请日: 1984-09-12
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公开(公告)号: US4575504A公开(公告)日: 1986-03-11
- 发明人: Robert Sauter , Gerhart Griss, deceased , Wolfgang Grell , Rudolf Hurnaus , Walter Kobinger , Ludwig Pichler
- 申请人: Robert Sauter , Gerhart Griss, deceased , Wolfgang Grell , Rudolf Hurnaus , Walter Kobinger , Ludwig Pichler
- 申请人地址: DEX Biberach an der Riss
- 专利权人: Dr. Karl Thomae GmbH
- 当前专利权人: Dr. Karl Thomae GmbH
- 当前专利权人地址: DEX Biberach an der Riss
- 优先权: DEX3230696 19820818
- 主分类号: A61K31/435
- IPC分类号: A61K31/435 ; A61K31/55 ; A61P9/06 ; C07D495/04 ; C07D513/14 ; A61K31/44
摘要:
Compounds of the formula ##STR1## wherein A is ##STR2## and R is hydrogen, alkyl of 1 to 5 carbon atoms, alkanoyl of 1 to 5 carbon atoms, alkenyl of 3 to 5 carbon atoms, (alkoxy of 1 to 4 carbon atoms)carbonyl, or aralkyl of 7 to 11 carbon atoms optionally halo-substituted,and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
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