发明授权
- 专利标题： Pharmaceutical compositions containing insulin
- 专利标题（中）： 含有胰岛素的药物组合物
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申请号： US608462申请日： 1984-05-09
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公开(公告)号： US4579730A公开(公告)日： 1986-04-01
- 发明人: Miriam Kidron , Ehud Ziv , Hanoch Bar-On , Amiram Eldor
- 申请人： Miriam Kidron , Ehud Ziv , Hanoch Bar-On , Amiram Eldor
- 申请人地址： ILX
- 专利权人： Hadassah Medical Organization
- 当前专利权人： Hadassah Medical Organization
- 当前专利权人地址： ILX
- 优先权： ILX68769 19830523
- 主分类号： A61K31/575
- IPC分类号： A61K31/575 ; A61K9/20 ; A61K9/28 ; A61K38/00 ; A61K38/16 ; A61K38/28 ; A61K38/55 ; A61K47/12 ; A61K47/14 ; A61K47/22 ; A61K9/50 ; A61K37/26
摘要：
The invention provides a pharmaceutical composition for the oral administration of insulin comprising insulin, a bile acid or alkali metal salt thereof, the bile acid being selected from the group consisting of cholic acid, chenodeoxycholic acid, taurocholic acid, taurochenodeoxycholic acid, glycocholic acid, glycochenocholic acid, 3.beta.-hydroxy-12-ketocholic acid, 12.alpha.-3.beta.-dihydrocholic acid, and ursodesoxycholic acid, and a protease inhibitor, the composition being provided with an enterocoating to assure passage through the stomach and release in the intestine.
公开/授权文献
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