发明授权
- 专利标题： Benzothiazepine derivatives
- 专利标题（中）： 苯并硫氮杂衍生物
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申请号： US746904申请日： 1985-06-20
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公开(公告)号： US4584131A公开(公告)日： 1986-04-22
- 发明人: David Floyd , John Krapcho
- 申请人： David Floyd , John Krapcho
- 申请人地址： NJ Princeton
- 专利权人： E. R. Squibb & Sons, Inc.
- 当前专利权人： E. R. Squibb & Sons, Inc.
- 当前专利权人地址： NJ Princeton
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/554 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; C07D281/10
摘要：
Vasodilating activity is exhibited by compounds having the formula ##STR1## n is 2 or 3; X is oxygen or sulfur;R.sub.1 and R.sub.2 are each independently hydrogen alkyl, cycloalkyl, or allyl, or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached are pyrrolidinyl, piperidinyl, or morpholinyl;R.sub.3 is alkyl, alkoxy, halogen, trifluoromethyl, or nitro;R.sub.4 is hydrogen, halogen, trifluoromethyl, or nitro; andR.sub.5 and R.sub.6 are each independently alkyl or cycloalkyl or R.sub.5 and R.sub.6 together with the nitrogen atom to which they are attached are pyrrolidinyl, piperidinyl, or morpholinyl.
公开/授权文献
- US5890153A Database lock control method 公开/授权日：1999-03-30
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