发明授权
- 专利标题: Bis-amidines
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申请号: US787547申请日: 1985-10-15
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公开(公告)号: US4590074A公开(公告)日: 1986-05-20
- 发明人: Dolatrai M. Vyas , Takushi Kaneko , Terrence W. Doyle
- 申请人: Dolatrai M. Vyas , Takushi Kaneko , Terrence W. Doyle
- 申请人地址: NY New York
- 专利权人: Bristol-Myers Company
- 当前专利权人: Bristol-Myers Company
- 当前专利权人地址: NY New York
- 主分类号: C07D487/14
- IPC分类号: C07D487/14 ; A61K31/40 ; C07D403/04
摘要:
Symmetrical bis-amidine derivatives of mitomycin C may be converted to unsymmetrical bis-amidine analogs by reaction with secondary amines. The compounds are active anti-tumor agents in experimental animal tumors.
公开/授权文献
- US5783567A Microparticles for delivery of nucleic acid 公开/授权日:1998-07-21
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