发明授权
- 专利标题: Hydroxamates
- 专利标题(中): 羟基磷灰石
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申请号: US720102申请日: 1985-04-04
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公开(公告)号: US4604407A公开(公告)日: 1986-08-05
- 发明人: Martin F. Haslanger , Donald S. Karanewsky
- 申请人: Martin F. Haslanger , Donald S. Karanewsky
- 申请人地址: NJ Princeton
- 专利权人: E. R. Squibb & Sons, Inc.
- 当前专利权人: E. R. Squibb & Sons, Inc.
- 当前专利权人地址: NJ Princeton
- 主分类号: A61K31/13
- IPC分类号: A61K31/13 ; A61K31/16 ; A61K31/165 ; A61K31/195 ; A61K31/215 ; A61P37/08 ; C07C67/00 ; C07C239/00 ; C07C259/06 ; C12N9/99 ; A61K31/185 ; C07C83/10
摘要:
Hydroxamates are provided having the structure ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, or ##STR2## wherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C.sub.1 -C.sub.4 -alkylamino or C.sub.1 -C.sub.4 -dialkylamino.R.sup.2 is hydrogen or lower alkyl; andR.sup.3 is C.sub.1 -C.sub.20 alkyl or C.sub.3 -C.sub.20 alkenyl, aryl, aryl-alkyl, cycloalkyl, aryl-alkenyl, lower alkoxy, lower alkenyloxy, aryl-alkoxy or cycloalkyloxy, and m is 0 to 5. These compounds are useful as inhibitors of .DELTA..sup.5 -lipoxygenase and as such are useful as antiallergy agents.
公开/授权文献
- US5235512A Self-tuning speed control for a vehicle 公开/授权日:1993-08-10
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