发明授权
US4607046A 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate and
pharmaceutical compositions
失效
4-（1-咪唑基甲基）肉桂酸盐酸盐一水合物和药物组合物
- 专利标题： 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate and pharmaceutical compositions
- 专利标题（中）： 4-（1-咪唑基甲基）肉桂酸盐酸盐一水合物和药物组合物
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申请号： US347616申请日： 1982-02-10
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公开(公告)号： US4607046A公开(公告)日： 1986-08-19
- 发明人: Kaname Morita , Shigeo Arikawa , Mitsuo Watanabe , Kinji Iizuka , Kenji Akahane
- 申请人： Kaname Morita , Shigeo Arikawa , Mitsuo Watanabe , Kinji Iizuka , Kenji Akahane
- 申请人地址： JPX both of JPX both of
- 专利权人： Kissei Pharmaceutical Co., Ltd.,Ono Pharmaceutical Co., Ltd.
- 当前专利权人： Kissei Pharmaceutical Co., Ltd.,Ono Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX both of JPX both of
- 优先权： JPX56-18488 19810210
- 主分类号： A61K31/415
- IPC分类号： A61K31/415 ; A61P7/02 ; C07D233/60 ; C07D521/00
摘要：
4-(1-Imidazolylmethyl)cinnamic acid hydrochloride monohydrate of the formula: ##STR1## and pharmaceutical compositions containing such compound. The imidazole derivative above has a strong and specific inhibitory effect on thromboxane synthetase from human or bovine platelet microsomes, and is useful as a therapeutical agent for inflammation, hypertension, thrombus, cerebral apoplexy, and asthma.
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