发明授权
US4618696A 9-oxo-15.alpha.-hydroxy-16-phenoxy and 16-substituted phenoxy
17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
失效
9-氧代-15α-羟基-16-苯氧基和16-取代的苯氧基17,18,19,20-四前驱体-4,5,13,(E) - 三烯酸酯
- 专利标题: 9-oxo-15.alpha.-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
- 专利标题(中): 9-氧代-15α-羟基-16-苯氧基和16-取代的苯氧基17,18,19,20-四前驱体-4,5,13,(E) - 三烯酸酯
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申请号: US636058申请日: 1984-07-31
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公开(公告)号: US4618696A公开(公告)日: 1986-10-21
- 发明人: Gary F. Cooper , John A. Edwards , Albert R. Van Horn
- 申请人: Gary F. Cooper , John A. Edwards , Albert R. Van Horn
- 申请人地址: CA Palo Alto
- 专利权人: Syntex (U.S.A.) Inc.
- 当前专利权人: Syntex (U.S.A.) Inc.
- 当前专利权人地址: CA Palo Alto
- 主分类号: A61K31/557
- IPC分类号: A61K31/557 ; A61K31/5575 ; A61P43/00 ; C07C67/00 ; C07C401/00 ; C07C405/00 ; C07C177/00
摘要:
This invention covers a compound of the formula ##STR1## wherein R is hydrogen, lower alkyl or a pharmaceutically acceptable, non-toxic salt of a compound wherein R is hydrogen; and X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy; and the wavy lines represent the .alpha. or .beta. configuration with the proviso that when one wavy line is .alpha. the other is .beta..
公开/授权文献
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