发明授权
- 专利标题: 3-aryl-3-pyrroline derivatives
- 专利标题(中): 3-芳基-3-吡咯啉衍生物
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申请号: US637351申请日: 1984-08-03
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公开(公告)号: US4626546A公开(公告)日: 1986-12-02
- 发明人: Gerhard Satzinger , Karl Mannhardt , Johannes Hartenstein , Manfred Herrmann , Edgar Fritschi , Wolfgang Steinbrecher
- 申请人: Gerhard Satzinger , Karl Mannhardt , Johannes Hartenstein , Manfred Herrmann , Edgar Fritschi , Wolfgang Steinbrecher
- 申请人地址: NJ Morris Plains
- 专利权人: Warner-Lambert Company
- 当前专利权人: Warner-Lambert Company
- 当前专利权人地址: NJ Morris Plains
- 优先权: DEX3328643 19830809
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61P9/08 ; A61P9/10 ; C07D207/20
摘要:
The invention is concerned with partially new compounds of the general formula ##STR1## wherein R.sup.1 is a hydrogen atom or an alkyl group with up to four carbon atoms and R.sup.2 a substituted phenyl radical and the pharmacologically acceptable salts thereof.The compounds can be prepared according to known procedures and show surprisingly a cardiovascular efficacy. They are capable of decompensating cardiac insufficiencies to a large extent. In addition to the new compounds, claim is also made for pharmaceutical compositions which contain compounds according to the general formula and their application for controlling cardiac and vascular diseases.
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