发明授权
- 专利标题： Ergoline carboxamides
- 专利标题（中）： 二氢吡啶甲酰胺
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申请号： US484477申请日： 1983-04-13
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公开(公告)号： US4632990A公开(公告)日： 1986-12-30
- 发明人: Luigi Bernardi , Enzo Brambilla , Laura Chiodini , Enrico di Salle , Daniela Ruggieri , Osvaldo Sapini , Aldemio Temperilli
- 申请人： Luigi Bernardi , Enzo Brambilla , Laura Chiodini , Enrico di Salle , Daniela Ruggieri , Osvaldo Sapini , Aldemio Temperilli
- 申请人地址： ITX Milan
- 专利权人： Farmitalia Carlo Erba S.p.A.
- 当前专利权人： Farmitalia Carlo Erba S.p.A.
- 当前专利权人地址： ITX Milan
- 优先权： GBX8210697 19820413
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61P13/02 ; A61P15/00 ; A61P25/00 ; A61P43/00 ; C07D457/02 ; C07D457/06 ; A61K31/48 ; C07D239/42
摘要：
There are provided ergoline derivatives of the formula: ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group, R.sub.2 represents a hydrogen or halogen atom or a methyl group, R.sub.3 represents a hydrogen atom or a methoxy group, R.sub.4 represents a hydrocarbon group having from 1 to 4 carbon atoms; each of X and W independently represents a hydrogen atom, a methyl group, a chlorine atom or a methoxy group, and n is 0, 1 or 2. A method for their preparation is also provided. The compounds have strong antiprolactin activity.
公开/授权文献
- US5702927A Process for preparation of purified xanthan gum 公开/授权日：1997-12-30