发明授权
- 专利标题: 2-phenyl-imidazo-pyrazines, useful as cardiotonics
- 专利标题(中): 2-苯基 - 咪唑并吡嗪,可用作强心剂
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申请号: US675299申请日: 1984-11-27
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公开(公告)号: US4656171A公开(公告)日: 1987-04-07
- 发明人: Volkhard Austel , Norbert Hauel , Joachim Heider , Manfred Reiffen , Jacobus C. A. Van Meel , Willi Diederen
- 申请人: Volkhard Austel , Norbert Hauel , Joachim Heider , Manfred Reiffen , Jacobus C. A. Van Meel , Willi Diederen
- 申请人地址: DEX Biberach an der Riss
- 专利权人: Dr. Karl Thomae GmbH
- 当前专利权人: Dr. Karl Thomae GmbH
- 当前专利权人地址: DEX Biberach an der Riss
- 优先权: DEX3346640 19831223
- 主分类号: A61K31/50
- IPC分类号: A61K31/50 ; A61K31/53 ; A61P9/02 ; A61P9/04 ; C07D487/04 ; A61K31/495 ; C07D471/02
摘要:
Compounds of the formula ##STR1## wherein A, B, C and D are each independently --N.dbd. or --CH.dbd., provided, however, that at least two of them must be --N.dbd., and when A and C are both --N.dbd., at least one or both of B and D must be --N.dbd.; andR.sub.1, R.sub.2 and R.sub.3 are substituents of diverse types;tautomers thereof; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds are useful as cardiotonics.
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