A polyamide-rubber blend composition is disclosed. The composition is prepared by mixing the following components (a) and (b) under heating in the presence of a crosslinking agent.(a) 70 to 40 vol % of a rubber composition made of 5 to 40 vol % of an acrylonitrile-butadiene copolymer rubber and 95 to 50 vol % of an epichlorohydrin rubber; and(b) 30 to 60 vol % of a polyamide resin, the gel fraction of the rubber composition (a) in the blend composition is at least 70 wt %.The acrylonitrile-butadiene copolymer rubber of the composition preferably contains not less than 1.5 wt % of a carboxyl group in the polymer.