发明授权
US4670438A Imidazo[4,5-c]pyridazine-3-ones, imidazo[4,5-d]pyridazine-4-ones,
imidazo[4,]pyrazin-5-ones, purin-2-ones, purin-6-ones, and
purin-2,6-diones useful as hypotensive or cardiotonic agents
失效
咪唑并[4,5-c]哒嗪-3-酮,咪唑并[4,5-d]哒嗪-4-酮,咪唑并[4,5-b]吡嗪-5-酮,嘌呤-2-酮, 6-酮和嘌呤-2,6-二酮可用作降血压或强心剂
- 专利标题: Imidazo[4,5-c]pyridazine-3-ones, imidazo[4,5-d]pyridazine-4-ones, imidazo[4,]pyrazin-5-ones, purin-2-ones, purin-6-ones, and purin-2,6-diones useful as hypotensive or cardiotonic agents
- 专利标题(中): 咪唑并[4,5-c]哒嗪-3-酮,咪唑并[4,5-d]哒嗪-4-酮,咪唑并[4,5-b]吡嗪-5-酮,嘌呤-2-酮, 6-酮和嘌呤-2,6-二酮可用作降血压或强心剂
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申请号: US623718申请日: 1984-06-22
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公开(公告)号: US4670438A公开(公告)日: 1987-06-02
- 发明人: Volkhard Austel , Joachim Heider , Norbert Hauel , Manfred Reiffen , Jacobus C. A. van Meel , Willi Diederen
- 申请人: Volkhard Austel , Joachim Heider , Norbert Hauel , Manfred Reiffen , Jacobus C. A. van Meel , Willi Diederen
- 申请人地址: DEX Biberach an der Riss
- 专利权人: Dr. Karl Thomae GmbH
- 当前专利权人: Dr. Karl Thomae GmbH
- 当前专利权人地址: DEX Biberach an der Riss
- 优先权: DEX3324115 19830705
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/50 ; A61K31/52 ; A61K31/522 ; A61K31/53 ; A61P9/04 ; A61P9/12 ; C07D471/04 ; C07D473/02 ; C07D473/04 ; C07D473/08 ; C07D473/28 ; C07D473/30 ; C07D473/40 ; C07D487/04 ; A61K31/495
摘要:
Compounds of the formula ##STR1## wherein A, B, C and D are --N.dbd., HN.dbd., R.sub.3 N.dbd., O.dbd.C.dbd., HC.tbd., HO--C.tbd. or R.sub.3 SO.sub.2 --O--C.tbd.; andR.sub.1 and R.sub.2 are substituents of various types.The compounds are useful as hypotensives and cardiotonics.
公开/授权文献
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