发明授权
US4673685A Hydroximic acids of 7-oxabicycloheptane substituted ethers and
thioethers useful in the treatment of thrombotic disease
失效
可用于治疗血栓性疾病的7-氧杂双环庚烷取代的醚和硫醚的羟基酸
- 专利标题： Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease
- 专利标题（中）： 可用于治疗血栓性疾病的7-氧杂双环庚烷取代的醚和硫醚的羟基酸
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申请号： US888671申请日： 1986-07-23
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公开(公告)号： US4673685A公开(公告)日： 1987-06-16
- 发明人: Ravi K. Varma , Eric M. Gordon , Ligaya M. Simpkins
- 申请人： Ravi K. Varma , Eric M. Gordon , Ligaya M. Simpkins
- 申请人地址： NJ Princeton
- 专利权人： E. R. Squibb & Sons, Inc.
- 当前专利权人： E. R. Squibb & Sons, Inc.
- 当前专利权人地址： NJ Princeton
- 主分类号： A61K31/34
- IPC分类号： A61K31/34 ; A61K31/44 ; A61P1/04 ; A61P7/02 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P11/08 ; A61P17/00 ; A61P25/04 ; A61P29/00 ; A61P37/08 ; A61P43/00 ; C07D493/08 ; A61K31/557 ; C07D307/00
摘要：
Hydroximic acids of 7-oxabicycloheptane substituted ether and thioether prostaglandin analogs are provided having the structural formula ##STR1## wherein Y is O or ##STR2## and including all stereoisomers thereof. The compounds are inhibitors of prostaglandin and biosynthesis and as such are useful, for example, as anti-allergy and antiinflammatory agents and also as antipsoriatic agents.
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