发明授权
US4686208A Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates
and method of use
失效
磷酸化糖基酰胺, - 脲, - 氨基甲酸酯和 - 硫代氨基甲酸酯及其使用方法
- 专利标题: Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates and method of use
- 专利标题(中): 磷酸化糖基酰胺, - 脲, - 氨基甲酸酯和 - 硫代氨基甲酸酯及其使用方法
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申请号: US673811申请日: 1984-11-21
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公开(公告)号: US4686208A公开(公告)日: 1987-08-11
- 发明人: Oswald Lockhoff , Bernd-Wieland Kruger , Peter Stadler , Arnold Paessens , Gert Streissle , Peter Taylor , Hans-Joachim Zeiler , Karl-Georg Metzger
- 申请人: Oswald Lockhoff , Bernd-Wieland Kruger , Peter Stadler , Arnold Paessens , Gert Streissle , Peter Taylor , Hans-Joachim Zeiler , Karl-Georg Metzger
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX3342308 19831123; DEX3403495 19840202
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; C07H13/06 ; C07H13/12 ; C07H5/06
摘要:
Compounds of the formula ##STR1## in which R.sup.1 represents an optionally substituted, straight-chain or branched, saturated, monounsaturated or polyunsaturated alkyl radical, an optionally substituted, saturated or one- or polyunsaturated cycloalkyl radical or an optionally substituted aryl radical or aralkyl radical,X represents CH.sub.2, O, S, NH or N-alkyl with up to 20 C atoms,R.sup.2 has the meaning of R.sup.1, and can represent hydrogen if X denotes CH.sub.2, the radicals R.sup.3 independently of one another represent hydrogen, an acyl radical or alkyl radical with in each case up to 20 C atoms, a silyl radical and/or a phosphoric acid or phosphoric acid ester radical andR.sup.4 denotes hydrogen, methyl or --CH.sub.2 --OR.sup.3, with the proviso that one of the radicals R.sup.3 always represents a phosphoric acid or phosphoric acid ester radical, which stimulate a patient's immune system and are thereby effective in combating viral disease and bacterial infection.
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