发明授权
US4689329A 5-substituted octahydroindolizine analgesics compounds and 7-keto
intermediates
失效
5-取代八氢吲哚啉镇痛药和7-酮中间体
- 专利标题： 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates
- 专利标题（中）： 5-取代八氢吲哚啉镇痛药和7-酮中间体
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申请号： US826167申请日： 1986-02-04
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公开(公告)号： US4689329A公开(公告)日： 1987-08-25
- 发明人: Richard J. Carmosin , John R. Carson
- 申请人： Richard J. Carmosin , John R. Carson
- 申请人地址： PA Fort Washington
- 专利权人： McNeilab, Inc.
- 当前专利权人： McNeilab, Inc.
- 当前专利权人地址： PA Fort Washington
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61P25/04 ; C07D471/04 ; A61K31/40
摘要：
Octahydroindolizidines and corresponding ketones of the formulae (I) and (II): ##STR1## where A is a 3-7 carbon or hetero-containing ring, R.sup.1 is a substituent, n is 0-6 and x is 0-3. Also, pharmaceutical compositions for treating pain containing (I) or (II) and methods for synthesis and use as well as novel intermediates in the synthesis. A
公开/授权文献
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