发明授权
US4695552A Process and reagent for the determination of the hemoglobin-haptoglobin
complex in the presence of free hemoglobin
失效
在游离血红蛋白存在下测定血红蛋白 - 触珠蛋白复合物的方法和试剂
- 专利标题: Process and reagent for the determination of the hemoglobin-haptoglobin complex in the presence of free hemoglobin
- 专利标题(中): 在游离血红蛋白存在下测定血红蛋白 - 触珠蛋白复合物的方法和试剂
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申请号: US601801申请日: 1984-04-19
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公开(公告)号: US4695552A公开(公告)日: 1987-09-22
- 发明人: Urban Schmitt , Rolf Deeg , Joachim Ziegenhorn
- 申请人: Urban Schmitt , Rolf Deeg , Joachim Ziegenhorn
- 申请人地址: DEX Mannheim
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DEX Mannheim
- 优先权: DEX3314308 19830420
- 主分类号: C12Q1/28
- IPC分类号: C12Q1/28 ; G01N33/72
摘要:
The present invention provides a process for the determination of the hemoglobin-haptoglobin complex in the presence of free hemoglobin by utilization of the different peroxidate properties of free and of bound hemoglobin, wherein, for the selective inhibition of the peroxidase activity of the free hemoglobin, a detergent is added and the residual peroxidate activity of the reaction mixture is measured.The present invention also provides a reagent for carrying out this process wherein, besides the substances required for the determination of the peroxidase activity, it contains a detergent for the inhibition of the peroxidase activity of free hemoglobin.Furthermore, the present invention provides a process for determining the haptoglobin content of a sample, as well as a process for determining glycosilated hemoglobin in a sample.
公开/授权文献
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