The single acoustic box with spatial effect for stereophonic musical reproduction systems, according to the invention, consists of an outer shell having at the top a loudspeaker for low-frequency sounds and on the lateral walls at least two loudspeakers for medium- and high-frequency sounds, positioned opposite to each other, and is equipped with a separating circuit having two inputs connectable to an amplifier of a stereophonic musical reproduction system and several outputs for low-frequency signals, unified and connected to the loudspeaker for low-frequency sounds and for high-frequency signals, divided between the two stereophonic reproduction channels, connected to two or more loudspeakers for medium - and high frequencies.The spatial effect is perceived by the listener due to the multiple reflections of the acoustic waves against the walls of the installation site.