发明授权
US4725606A 2-benzyl-4-(4-pyridyl)thiazoles and derivatives thereof as
immunoregulants and compositions
失效
2-苄基-4-(4-吡啶基)噻唑及其衍生物作为免疫调节剂和组合物
- 专利标题: 2-benzyl-4-(4-pyridyl)thiazoles and derivatives thereof as immunoregulants and compositions
- 专利标题(中): 2-苄基-4-(4-吡啶基)噻唑及其衍生物作为免疫调节剂和组合物
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申请号: US899314申请日: 1986-08-21
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公开(公告)号: US4725606A公开(公告)日: 1988-02-16
- 发明人: David A. Boulton , Vernon L. Moore , Ihor E. Kopka , Arsenio A. Pessolano
- 申请人: David A. Boulton , Vernon L. Moore , Ihor E. Kopka , Arsenio A. Pessolano
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07D213/50
- IPC分类号: C07D213/50 ; C07D213/65 ; C07D417/04 ; A61K31/44
摘要:
2-Benzyl-4-(4-pyridyl)thiazoles and derivatives thereof have been made from converting a benzyl cyanide to the corresponding thioamide followed by condensation with a 4-bromoacetylpyridine. The thiazole derivatives are found to be effective immunoregulants.