发明授权
US4728656A 2,2-alkyldiylbis(thio)bis(imidazoles) useful for inhibition of the
5-lipoxygenase pathway
失效
可用于抑制5-脂肪氧合酶途径的2,2-二烷基二基双(硫代)双(咪唑)
- 专利标题: 2,2-alkyldiylbis(thio)bis(imidazoles) useful for inhibition of the 5-lipoxygenase pathway
- 专利标题(中): 可用于抑制5-脂肪氧合酶途径的2,2-二烷基二基双(硫代)双(咪唑)
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申请号: US856735申请日: 1986-04-28
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公开(公告)号: US4728656A公开(公告)日: 1988-03-01
- 发明人: Paul E. Bender , David T. Hill
- 申请人: Paul E. Bender , David T. Hill
- 申请人地址: PA Philadelphia
- 专利权人: SmithKline Beckman Corporation
- 当前专利权人: SmithKline Beckman Corporation
- 当前专利权人地址: PA Philadelphia
- 主分类号: C12N9/99
- IPC分类号: C12N9/99 ; A61K31/415 ; A61K31/44 ; A61K31/4427 ; A61P29/00 ; A61P43/00 ; C07D233/84 ; C07D401/12 ; C07D401/14
摘要:
Novel compounds, pharmaceutical compositions and a method of inhibiting the 5-lipoxygenase products in an animal in need thereof which comprises administering an effective, 5-lipoxygenase pathway inhibiting amount of a 2,2'-[1,2-ethanediylbis-(thio)]-bis-1H-imidazole or 2,2'-[(1,3-propan-2-onediylbis-(thio)]bis-1H-imidazole, or a pharmaceutically acceptable salt thereof, to such animal.