发明授权
- 专利标题: Liposome extrusion method
- 专利标题(中): 脂质体挤出法
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申请号: US829710申请日: 1986-02-13
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公开(公告)号: US4737323A公开(公告)日: 1988-04-12
- 发明人: Francis J. Martin , Jacqueline K. Morano
- 申请人: Francis J. Martin , Jacqueline K. Morano
- 申请人地址: CA Menlo Park
- 专利权人: Liposome Technology, Inc.
- 当前专利权人: Liposome Technology, Inc.
- 当前专利权人地址: CA Menlo Park
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/127 ; B01J13/02 ; C04B38/00 ; A61K9/52
摘要:
A suspension of liposomes whose sizes are predominantly greater than about 1 micron is passed through an asymmetric ceramic filter whose inner-surface pore size is about 1 micron. The processed liposomes have a selected average size of about 0.4 microns or less, depending on the number of filter cycles, and a narrow distribution.
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