发明授权
- 专利标题: Phosphoric esters and process for preparing same
- 专利标题(中): 磷酸酯及其制备方法
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申请号: US878681申请日: 1986-06-26
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公开(公告)号: US4740609A公开(公告)日: 1988-04-26
- 发明人: Junya Watatsuki , Tohru Katoh , Tomihiro Kurosaki
- 申请人: Junya Watatsuki , Tohru Katoh , Tomihiro Kurosaki
- 申请人地址: JPX Tokyo
- 专利权人: Kao Corporation
- 当前专利权人: Kao Corporation
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX60-169513 19850731
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; B01F17/14 ; C07F9/09 ; C08F30/02 ; C11D3/36 ; C07F9/11
摘要:
Novel phosphoric esters of the general formula ##STR1## in which X represents a halogen, R.sub.1 represents a linear or branched alkyl, fluoroalkyl or alkenyl group having from 1 to 36 carbon atoms, or a phenyl group substituted with a linear or branched alkyl group having from 1 to 15 carbon atoms, R.sub.2 represents an alkylene group having 2 or 3 carbon atoms, n is a value of from 0 to 30, and M represents a hydrogen atom, alkali metal, alkaline earth metal, ammonium, or an alkylamine or alkanolamine salt are prepared by reacting a salt of a phosphoric monoester of the general formula (II) ##STR2## in which R.sub.1, R.sub.2 and n have, respectively, the same meanings as defined above, and M.sub.1 represents an alkali metal, with an epihalohydrin of the general formula (III) ##STR3## in which X has the same meaning as defined above, and optionally, converting the resulting product into a free acid or a different salt.The phosphoric esters are reacted with a trialkylamine to readily obtain phospholipid simulants having a quaternary ammonium salt in a molecule thereof. When an alkali is acted on the phosphoric esters, the dehydrohalogenation reaction takes place and the esters are converted into a phosphoric ester having a polymerizable group.
公开/授权文献
- US4160560A Sliding door lock assembly 公开/授权日:1979-07-10