发明授权
- 专利标题: Method for preparing small vesicles using microemulsification
- 专利标题(中): 使用微乳液制备小囊泡的方法
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申请号: US696727申请日: 1985-01-31
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公开(公告)号: US4753788A公开(公告)日: 1988-06-28
- 发明人: Ronald C. Gamble
- 申请人: Ronald C. Gamble
- 申请人地址: CA Pasadena
- 专利权人: Vestar Research Inc.
- 当前专利权人: Vestar Research Inc.
- 当前专利权人地址: CA Pasadena
- 主分类号: A61K51/00
- IPC分类号: A61K51/00 ; A61K9/10 ; A61K9/127 ; A61K9/133 ; A61K45/08 ; B01J13/00 ; B01J13/02 ; A61K43/00 ; A61K49/00
摘要:
A method is provided for preparing small (less than 2000 .ANG.) lipid vesicles in commercial quantities by microemulsifying lipid compositions using very high shear forces generated in a homogenizing apparatus operated at high pressures at a selected temperature. These vesicles are suitable for various biological applications including targeting of tumors in a body for diagnosis and treatment.
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