发明授权
US4758437A Composition for long acting nicardipine preparation and process of
producing the composition
失效
用于长效尼卡地平制剂的组合物和制备组合物的方法
- 专利标题： Composition for long acting nicardipine preparation and process of producing the composition
- 专利标题（中）： 用于长效尼卡地平制剂的组合物和制备组合物的方法
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申请号： US13326申请日： 1987-02-11
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公开(公告)号： US4758437A公开(公告)日： 1988-07-19
- 发明人: Takashi Sonobe , Hiroitsu Kawata , Masayoshi Aruga , Tadayoshi Ohmura , Satoru Yoneya , Chiharu Yamada , Yukio Kubota
- 申请人： Takashi Sonobe , Hiroitsu Kawata , Masayoshi Aruga , Tadayoshi Ohmura , Satoru Yoneya , Chiharu Yamada , Yukio Kubota
- 申请人地址： JPX Tokyo
- 专利权人： Yamanouchi Pharmaceutical Co., Ltd.
- 当前专利权人： Yamanouchi Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 主分类号： A61K9/50
- IPC分类号： A61K9/50 ; A61K31/44 ; A61K9/14 ; A61K9/16 ; A61K9/20 ; A61K31/74
摘要：
A spherical pellet like composition of nicardipine composed of small granular nuclei such as sugar particles coated with amorphous nicardipine or a salt thereof, a pH-dependent additive and a surface active agent. The spherical pellet like composition of nicardipine may have a further coating of a medicament permeating material as an outermost coating. The spherical pellet like composition may be mixed with the spherical pellet like composition coated with the medicament permeating material.
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