发明授权
- 专利标题: Amino substituted benzenepropanols
- 专利标题(中): 氨基取代苯丙酰醇
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申请号: US726549申请日: 1985-04-24
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公开(公告)号: US4788010A公开(公告)日: 1988-11-29
- 发明人: David M. Floyd , Spencer D. Kimball , Steven Brandt
- 申请人: David M. Floyd , Spencer D. Kimball , Steven Brandt
- 申请人地址: NJ Princeton
- 专利权人: E. R. Squibb & Sons, Inc.
- 当前专利权人: E. R. Squibb & Sons, Inc.
- 当前专利权人地址: NJ Princeton
- 主分类号: C07C91/16
- IPC分类号: C07C91/16 ; C07C93/08
摘要:
Hypotensive activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1 is hydrogen or alkyl;R.sub.2 and R.sub.3 are each independently phenyl, substituted phenyl, cycloalkyl, or R.sub.2 is hydrogen and R.sub.3 is heteroaryl;R.sub.4 and R.sub.5 are the same or different and each is hydrogen, hydroxy, alkoxy, alkanoyl or alkyl;R.sub.6 is hydrogen or alkyl; andn is 1, 2, 3 or 4; with the proviso that if R.sub.2 and R.sub.3 are each phenyl, at least one of R.sub.1, R.sub.4, R.sub.5 and R.sub.6 is other than hydrogen.
公开/授权文献
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