An electrophotographic lithographic printing plate precursor is disclosed, comprising a conductive support having provided thereon at least one photoconductive layer containing photoconductive zinc oxide and a resin binder, wherein said resin binder comprises a resin containing at least one functional group capable of forming a carboxylic acid upon being decomposed. The printing plate precursor forms an image faithful to an original and causes no background stains because of improved oil-insensitivity of non-image areas, and a printing plate obtained therefrom exhibits high stain resistance and printing durability.