发明授权
US4816442A Method of inhibiting tumor growth sensitive to CIF-.beta.treatment
失效
抑制对CIF-β治疗敏感的肿瘤生长的方法
- 专利标题： Method of inhibiting tumor growth sensitive to CIF-.beta.treatment
- 专利标题（中）： 抑制对CIF-β治疗敏感的肿瘤生长的方法
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申请号： US928760申请日： 1986-11-07
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公开(公告)号： US4816442A公开(公告)日： 1989-03-28
- 发明人: John M. McPherson , Danile R. Twardzik , George J. Todaro , Karl A. Piez , Jane E. Ranchalis
- 申请人： John M. McPherson , Danile R. Twardzik , George J. Todaro , Karl A. Piez , Jane E. Ranchalis
- 申请人地址： CA Palo Alto
- 专利权人： Collagen Corporation
- 当前专利权人： Collagen Corporation
- 当前专利权人地址： CA Palo Alto
- 主分类号： A61K38/22
- IPC分类号： A61K38/22 ; A61K38/00 ; A61K38/18 ; A61P35/00 ; A61K37/00
摘要：
Polypeptides called cartilage-inducing factors (CIFs) that are found in bone and have heretofore been identified as having in vitro cartilage-inducing activity. TGF-.beta. activity, and anti-inflammatory activity have now been found to possess potent oncostatic activity. The CIFs showed oncostatic activity on human and animal tumors, including carcinomas, adenocarcinomas, lymphomas, and melanomas.
公开/授权文献
- US5916436A Drain trap 公开/授权日：1999-06-29
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