发明授权
- 专利标题: 1-Sulfo-2-oxoazetidine derivatives and their production
- 专利标题(中): 1-磺基-2-氧代氮杂环丁烷衍生物及其制备
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申请号: US326939申请日: 1981-12-03
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公开(公告)号: US4822790A公开(公告)日: 1989-04-18
- 发明人: Michihiko Ochiai , Taisuke Matsuo
- 申请人: Michihiko Ochiai , Taisuke Matsuo
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: WOXPCT/JP80/00296 19801205; WOXPCT/JP81/00102 19810430; WOXPCT/JP81/00192 19810825
- 主分类号: C07D205/08
- IPC分类号: C07D205/08 ; A61K31/395 ; A61K31/397 ; A61K31/41 ; A61K31/425 ; A61K31/44 ; A61K31/4427 ; A61K31/4433 ; A61K31/495 ; A61P31/04 ; C07D205/00 ; C07D205/085 ; C07D205/09 ; C07D205/095 ; C07D213/00 ; C07D233/00 ; C07D241/00 ; C07D261/00 ; C07D333/00 ; C07D401/12 ; C07D403/12 ; C07D409/12 ; C07D409/14 ; C07D413/12 ; C07D417/12 ; C07D417/14 ; C07F7/08 ; C07F7/10 ; C07F9/568
摘要:
Disclosed are compounds of the general formula: ##STR1## wherein R.sub.1 is amino, an acylated amino or a protected amino group, X is hydrogen or methoxy, and R' is hydrogen, R or R.sup.4 where R is an organic residue attached to the azetidine ring through a carbon atom therein and R.sub.4 is azido, a halogen, an amino group which may optionally be acylated or a group of the formula ##STR2## wherein R.sub.5 is an organic residue and n is 0, 1 or 2, and pharmaceutically acceptable salts and esters thereof.The compounds have antimicrobial and/or .beta.-lactamase-inhibitory activity and are of value as drugs for human beings and domesticated animals.
公开/授权文献
- US5603488A Rail attachable rescue frame for rail bridges 公开/授权日:1997-02-18