发明授权
- 专利标题： N-substituted derivatives of 1-desaminovasopressin
- 专利标题（中）： 1-取代氨基加压素的N-取代衍生物
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申请号： US672167申请日： 1984-11-16
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公开(公告)号： US4829051A公开(公告)日： 1989-05-09
- 发明人: Joseph H. Cort , Alan J. Fischman
- 申请人： Joseph H. Cort , Alan J. Fischman
- 申请人地址： AZ Tucson
- 专利权人： Vega Laboratories, Inc.
- 当前专利权人： Vega Laboratories, Inc.
- 当前专利权人地址： AZ Tucson
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K7/16
摘要：
Novel analogs of biologically active vasopressin and its synthetic analogs having improved activity are represented by the structural formula: ##STR1## wherein A hydrogen; is hydroxy or lower alkoxy, especially methoxy, B is the peptide residue of phenylalanine (Phe) or isoleucine, Gln represents the peptide residue of glutamine Asn represents the peptide residue of asparagine, E represents the peptide residue of proline (Pro), 4-thioproline (4-thioPro) or 3,4-dehydroproline (3,4-dehydroPro), FNH represents an N-substituted peptide residue of L- or D-lysine (Lys) L or D homolysine (h Lys) or L- or D-orntihine (Orn), X represents a side peptide chain consisting of one or more of Gly, L-Ala, L-Val, L-Leu, or L-Phe, Gly represents the peptide residue of glycine, and G is disulfide (--S--S--) or thioether (--CH.sub.2 S-- or --SCH.sub.2 --).
公开/授权文献
- US5614465A Method of making a color filter array by thermal transfer 公开/授权日：1997-03-25
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