An improved self-draining panel threshold combination for a panel such as a door or the like which is of simple design and construction, and passes industry air and water penetration requirements without the use of separate corner seals or door bottom seals. The door threshhold combination comprises weatherseals around the entire periphery of the door lying in a weatherseal plane. An open-ended water trough in the threshold extends from one jamb to the other and lies substantially in the weatherseal plane for catching any water that leaks into and past the weatherseals. The threshold has a weatherseal adjacent the water trough that is adapted when flexed by the closed door to allow entry of water into the open end of the water through, and when unflexed upon movement of the door to its open position to cover the open end to prevent foreign material from entering the trough. A drainage system is provided for draining water entering the water trough out of the threshold.