A scroll saw blade clamp and blade alignment tool to facilitate blade changes while assuring proper positioning and alignment of the blade. The blade clamp is for the upper end of the blade and includes a pair of clamp bars, one of which is pivoted to the upper saw arm. A locking screw clamps the bars together for clamping of the blade, and a strategically located pin prevents relative rotation of the clamp bars and also serves as a blade guide to properly locate the blade while it is being clamped in place. The alignment device takes the form of a flat bar provided with a recess for holding the lower blade clamp. A groove in the bar is centered on the recess to properly align a saw blade received in the groove.