发明授权
- 专利标题: Inhibitor of ribonucleotide reductase
- 专利标题(中): 核糖核苷酸还原酶抑制剂
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申请号: US53179申请日: 1987-05-22
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公开(公告)号: US4845195A公开(公告)日: 1989-07-04
- 发明人: Richard Colonno , Victor M. Garsky , John Hannah , Robert B. Stein , Richard L. Tolman
- 申请人: Richard Colonno , Victor M. Garsky , John Hannah , Robert B. Stein , Richard L. Tolman
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/035
摘要:
The pentapeptide Val Val Asn Asp Leu has been found to be the shortest peptide sequence that inhibits the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication. Longer peptides containing the foregoing pentapeptide sequence are more potent inhibitors.
公开/授权文献
- USD380578S Lamp base 公开/授权日:1997-07-01