发明授权
US4861886A Method for isomerization of trans-form 2-methylspiro (1,3-oxathiolane-5,3')
q
失效
异构化反式2-甲基螺（1,3-氧硫杂环戊烷-5,3'）奎宁环或其酸加成盐的方法
- 专利标题： Method for isomerization of trans-form 2-methylspiro (1,3-oxathiolane-5,3') q
- 专利标题（中）： 异构化反式2-甲基螺（1,3-氧硫杂环戊烷-5,3'）奎宁环或其酸加成盐的方法
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申请号： US215532申请日： 1988-07-06
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公开(公告)号： US4861886A公开(公告)日： 1989-08-29
- 发明人: Takahiro Haga , Itaru Shigehara , Toru Koyanagi , Kazutoshi Hara , Masaru Maeda
- 申请人： Takahiro Haga , Itaru Shigehara , Toru Koyanagi , Kazutoshi Hara , Masaru Maeda
- 申请人地址： JPX Osaka
- 专利权人： Ishahara Sangyo Kaisha Ltd
- 当前专利权人： Ishahara Sangyo Kaisha Ltd
- 当前专利权人地址： JPX Osaka
- 优先权： JPX62-172451 19870710; JPX62-180119 19870721; JPX62-202170 19870813; JPX63-7020 19880118
- 主分类号： C07D497/20
- IPC分类号： C07D497/20
摘要：
A method for isomerization of trans-form 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine or acid addition salts thereof, which comprises isomerizing said trans-form quinuclidine or acid addition salts thereof to cis-form 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine or acid addition salts thereof in the presence of at least one acid catalyst selected from the group consisting of an organic sulfuric acid, a halide functioning as a Lewis acid, and sulfuric acid.
公开/授权文献
- US6109709A Tool cabinet 公开/授权日：2000-08-29